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Four distinct genes encoding closely related FGF receptors FGF R1-4 are known All four genes for FGF Rs encode proteins with an N-terminal signal peptide three immunoglobulin (Ig)-like domains an acid box region containing a run of acidic residues between the IgI and IgII domains a transmembrane domain and the split tyrosine-kinase domain FGFR3 is tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of cell proliferation differentiation and apoptosis Plays an essential role in the regulation of chondrocyte differentiation proliferation and apoptosis and is required for normal skeleton development Regulates both osteogenesis and postnatal bone mineralization by osteoblasts
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Four distinct genes encoding closely related FGF receptors FGF R1 - 4 are known All four genes for FGF Rs encode proteins with an N-terminal signal peptide three immunoglobulin (Ig)-like domains an acid-box region containing a run of acidic residues between the IgI and IgII domains a transmembrane domain and the split tyrosine-kinase domain Multiple forms of FGF R1 - 3 are generated by alternative splicing of the mRNAs A frequent splicing event involving FGF R1 and 2 results in receptors containing all three Ig domains referred to as the alpha isoform or only IgII and IgIII referred to as the beta isoform
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Four distinct genes encoding closely related FGF receptors FGF R1-4 are known All four genes for FGF Rs encode proteins with an N-terminal signal peptide three immunoglobulin (Ig)-like domains an acid box region containing a run of acidic residues between the IgI and IgII domains a transmembrane domain and the split tyrosine-kinase domain FGFR3 is tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of cell proliferation differentiation and apoptosis
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HIV TAT specific factor 1 Primary Antibody Unconjugated Host Species Rabbit Target Species Human Mouse Clonality Monoclonal Applications WB IHC-P IHC-F IF(ICC) IP IF RecombinantConcentration 1ug/ul Size 100 ul Storage Buffer 10mM phosphate buffered saline(pH 7 4) with 150mM sodium chloride 0 05% BSA 0 02% sodium azide and 50% glycerol
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